Controlling multiple fluorescent signal output in cyclic peptide-based supramolecular systems

被引:61
作者
Brea, Roberto J.
Vazquez, M. Eugenio
Mosquera, Manuel
Castedo, Luis
Granja, Juan R. [1 ]
机构
[1] Univ Santiago de Compostela, Dept Quim Organ, Santiago De Compostela 15782, Spain
[2] Univ Santiago de Compostela, Dept Quim Fis, Santiago De Compostela 15782, Spain
关键词
D O I
10.1021/ja066885h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A multicomponent equilibrium network based on self-assembling alpha,gamma-cyclic peptides with controlled fluorescence output is described. The network takes advantage of the large association constant of alpha,gamma-cyclic peptides and the controlled formation homo- and heterodimers, making use for the first time of excimer/FRET effects in conjunction for studying complex interaction networks. In addition, we study the Dapoxyl/pyrene FRET pair for the first time.
引用
收藏
页码:1653 / 1657
页数:5
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