Towards erythropoietin mimicking small molecules

被引:9
作者
Doemling, Alexander
Beck, Barbara
Baumbach, William
Larbig, Gregor
机构
[1] ABC Pharma, D-81243 Munich, Germany
[2] Morphochem AG, D-81379 Munich, Germany
[3] Morphochem Inc, Monmouth Jct, NJ USA
关键词
IMCR; passerini; ugi; isocyanide; erythropoietin; design; combinatorial chemistry;
D O I
10.1016/j.bmcl.2006.10.040
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Small molecules potentially mimicking the hormone erythropoietin have been discovered by screening of a library of rationally designed multicomponent reaction molecules in a functional cell-based assay. (c) 2006 Published by Elsevier Ltd.
引用
收藏
页码:379 / 384
页数:6
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