Hydrolysis of oligonucleotides by homogeneous Ce(IV)/EDTA complex

被引：29

作者：

Igawa, T ^{[1
]}

Sumaoka, J ^{[1
]}

Komiyama, M ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Engn, Dept Chem & Biotechnol, Bunkyo Ku, Tokyo 1138656, Japan

来源：

CHEMISTRY LETTERS | 2000年 / 04期

关键词：

D O I：

10.1246/cl.2000.356

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Homogeneous Ce(IV) complex of EDTA promptly hydrolyzes oligonucleotides under physiological conditions. In contrast, dinucleotides are not hydrolyzed to measurable extents. The degree of polymerization of DNA substrate is crucial for the present catalysis.

引用

页码：356 / 357

页数：2

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