A macrocyclic receptor for the chiral recognition of hydroxycarboxylates

被引：81

作者：

Tejeda, A ^{[1
]}

Oliva, AI ^{[1
]}

Simón, L ^{[1
]}

Grande, M ^{[1
]}

Caballero, MC ^{[1
]}

Morán, JR ^{[1
]}

机构：

[1] Univ Salamanca, Dept Quim Organ, E-37008 Salamanca, Spain

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 23期

关键词：

macrocyclic hydrogen bonding receptor; chiral recognition; hydroxyacids; spirobifluorene; chromenone;

D O I：

10.1016/S0040-4039(00)00693-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Good chiral recognition of hydroxycarboxylates such as lactic or mandelic acids has been achieved with a macrocyclic receptor, readily available from a known bis-chromenylurea and a spirobifluorene linker. Resolution of the receptor racemic mixture was carried out taking advantage of its complexing properties with (R)-mandelic acid tetramethylammonium salt on a TLC plate. (C) 2000 Elsevier Science Ltd, All rights reserved.

引用

页码：4563 / 4566

页数：4

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