From alkyl halides to alkyltrifluoromethyls using bromine trifluoride

被引：26

作者：

Hagooly, A ^{[1
]}

Ben-David, I ^{[1
]}

Rozen, S ^{[1
]}

机构：

[1] Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 24期

关键词：

D O I：

10.1021/jo026128b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Under the right conditions, bromine trifluoride can be a useful tool for generating new types of reactions and compounds. Thus, tris(methylthio)alkyl derivatives, easily prepared from the corresponding alkyl bromides, were converted to the corresponding RCHBrCF2SMe or RCHBrCF3 compounds. The bromine atom, however, could be easily reduced forming eventually R'CF2SMe or R'CF3. If desired, the bromine atom can serve as an entry for constructing terminal difluoroolefins.

引用

页码：8430 / 8434

页数：5

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