Vitamin D deficiency in the intensive care unit: an invisible accomplice to morbidity and mortality?

被引：98

作者：

Lee, Paul ^{[1
,3
,5
]}

Nair, Priya ^{[2
]}

Eisman, John A. ^{[1
,3
,4
,5
]}

Center, Jacqueline R. ^{[1
,3
,4
,5
]}

机构：

[1] St Vincents Hosp, Dept Endocrinol, Sydney, NSW 2010, Australia

[2] St Vincents Hosp, Intens Care Unit, Sydney, NSW 2010, Australia

[3] Garvan Inst Med Res, Dept Endocrinol, Sydney, NSW 2010, Australia

[4] Garvan Inst Med Res, Bone & Mineral Res Programme, Sydney, NSW 2010, Australia

[5] Univ New S Wales, Sydney, NSW 2010, Australia

来源：

INTENSIVE CARE MEDICINE | 2009年 / 35卷 / 12期

关键词：

Endocrine disorders; Electrolyte disorders; Multiple organ failure; Nutrition; Systemic diseases; Cardiovascular issues in the ICU; Vitamin D deficiency; Hypocalcaemia; CRITICALLY ILL PATIENTS; PREDICTIVE-VALUE; HYPOCALCEMIA; 25-HYDROXYVITAMIN-D; REQUIREMENTS; ASSOCIATION; PREVALENCE; FAILURE; CALCIUM; DISEASE;

D O I：

10.1007/s00134-009-1642-x

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The association between vitamin D deficiency and chronic illness is well-known. Vitamin D deficiency has been associated with increased mortality in the general population. Despite this knowledge, vitamin D insufficiency is seldom considered and rarely replaced adequately, if at all, in critically ill patients in intensive care. We present a hypothetic model demonstrating how vitamin D deficiency may be an unrecognized contributor to adverse outcome in intensive care patients.

引用

页码：2028 / 2032

页数：5

共 37 条

[31] Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography [J].

Pilz, Stefan ;

Maerz, Winfried ;

Wellnitz, Britta ;

Seelhorst, Ursula ;

Fahrleitner-Pammer, Astrid ;

Dimai, Hans P. ;

Boehm, Bernhard O. ;

Dobnig, Harald .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2008, 93 (10) :3927-3935

[32] Low vitamin D levels predict stroke in patients referred to coronary angiography [J].

Pilz, Stefan ;

Dobnig, Harald ;

Fischer, Joachim E. ;

Wellnitz, Britta ;

Seelhorst, Ursula ;

Boehm, Bernhard O. ;

Maerz, Winfried .

STROKE, 2008, 39 (09) :2611-2613

[33] Bone turnover in prolonged critical illness: Effect of vitamin D [J].

Van den Berghe, G ;

Van Roosbroeck, D ;

Vanhove, P ;

Wouters, PJ ;

De Pourcq, L ;

Bouillon, R .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (10) :4623-4632

[34] HYPOCALCEMIA IN CRITICAL ILLNESS [J].

ZALOGA, GP ;

CHERNOW, B .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1986, 256 (14) :1924-1929

[35] ASSESSMENT OF CALCIUM HOMEOSTASIS IN THE CRITICALLY ILL SURGICAL PATIENT - THE DIAGNOSTIC PITFALLS OF THE MCLEAN-HASTINGS NOMOGRAM [J].

ZALOGA, GP ;

CHERNOW, B ;

COOK, D ;

SNYDER, R ;

CLAPPER, M ;

OBRIAN, JT .

ANNALS OF SURGERY, 1985, 202 (05) :587-594

[36] Hypocalcemia: A pervasive metabolic abnormality in the critically ill [J].

Zivin, JR ;

Gooley, T ;

Zager, RA ;

Ryan, MJ .

AMERICAN JOURNAL OF KIDNEY DISEASES, 2001, 37 (04) :689-698

[37] Vitamin D deficiency in undifferentiated connective tissue disease [J].

Zold, Eva ;

Szodoray, Peter ;

Gaal, Janos ;

Kappelmayer, Janos ;

Csathy, Laszlo ;

Gyimesi, Edit ;

Zeher, Margit ;

Szegedi, Gyula ;

Bodolay, Edit .

ARTHRITIS RESEARCH & THERAPY, 2008, 10 (05)

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