Structure of the O18 antigen from Acinetobacter baumannii

被引：14

作者：

Haseley, S ^{[1
]}

Wilkinson, SG ^{[1
]}

机构：

[1] UNIV HULL, SCH CHEM, KINGSTON UPON HULL HU6 7RX, N HUMBERSIDE, ENGLAND

来源：

CARBOHYDRATE RESEARCH | 1997年 / 301卷 / 3-4期

关键词：

Acinetobacter baumannii; lipopolysaccharide; O18; antigen; structure;

D O I：

10.1016/S0008-6215(97)00095-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The polymeric O antigen was obtained from lipopolysaccharide extracted from isolated, defatted cell walls of the reference strain for Acinetobacter baumannii serogroup O18. Monosaccharide analyses and NMR spectra established that the polymer had a regular structure with a repeating unit based on residues of D-galactose (2), N-acetyl-D-galactosamine (1), and N-acetyl-D-mannosamine (1). Further interpretation of the NMR spectra, combined with the results of methylation analysis and a Smith degradation, showed that the repeating unit had the following structure. [GRAPHICS] (C) 1997 Elsevier Science Ltd.

引用

页码：187 / 192

页数：6

共 21 条

[1] Acinetobacter spp, as nosocomial pathogens: Microbiological, clinical, and epidemiological features [J].

BergogneBerezin, E ;

Towner, KJ .

CLINICAL MICROBIOLOGY REVIEWS, 1996, 9 (02) :148-+

[2] Comparison of outbreak and nonoutbreak Acinetobacter baumannii strains by genotypic and phenotypic methods [J].

Dijkshoorn, L ;

Aucken, H ;

GernerSmidt, P ;

Janssen, P ;

Kaufmann, ME ;

Garaizar, J ;

Ursing, J ;

Pitt, TL .

JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (06) :1519-1525

[3] Acinetobacter species identification by using tRNA spacer fingerprinting [J].

Ehrenstein, B ;

Bernards, AT ;

Dijkshoorn, L ;

GernerSmidt, P ;

Towner, KJ ;

Bouvet, PJM ;

Daschner, FD ;

Grundmann, H .

JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (10) :2414-2420

[4] STRUCTURE OF A SURFACE POLYSACCHARIDE FROM ACINETOBACTER-BAUMANNII STRAIN-214 [J].

HASELEY, SR ;

GALBRAITH, L ;

WILKINSON, SG .

CARBOHYDRATE RESEARCH, 1994, 258 :199-206

[5] STRUCTURE OF THE PUTATIVE O-10 ANTIGEN FROM ACINETOBACTER-BAUMANNII [J].

HASELEY, SR ;

WILKINSON, SG .

CARBOHYDRATE RESEARCH, 1994, 264 (01) :73-81

[6] Structural studies of the putative O-specific polysaccharide of Acinetobacter baumannii 011 [J].

Haseley, SR ;

Wilkinson, SG .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1996, 237 (01) :266-271

[7] STRUCTURAL STUDIES OF THE PUTATIVE O-SPECIFIC POLYSACCHARIDE OF ACINETOBACTER-BAUMANNII O2 CONTAINING 3,6-DIDEOXY-3-N-(D-3-HYDROXYBUTYRYL)AMINO-D-GALACTOSE [J].

HASELEY, SR ;

WILKINSON, SG .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1995, 233 (03) :899-906

[8] Structure of a surface polysaccharide from Acinetobacter baumannii O16 [J].

Haseley, SR ;

Diggle, HJ ;

Wilkinson, SG .

CARBOHYDRATE RESEARCH, 1996, 293 (02) :259-265

[9] Structure of the O-specific polysaccharide of Acinetobacter baumannii 05 containing 2-acetamido-2-deoxy-D-galacturonic acid [J].

Haseley, SR ;

Wilkinson, SG .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1996, 237 (01) :229-233

[10]

HASELEY SR, IN PRESS EUR J BIOCH

← 1 2 3 →