Why chloroplasts and mitdchondria contain genomes

被引:65
作者
Allen, JF [1 ]
机构
[1] Lund Univ, Ctr Chem & Chem Engn, SE-22100 Lund, Sweden
来源
COMPARATIVE AND FUNCTIONAL GENOMICS | 2003年 / 4卷 / 01期
关键词
cytoplasmic organelles; photosynthesis; respiration; gene expression; electron transport; cell evolution; redox regulation; CORR; GENE-EXPRESSION; MITOCHONDRIAL GENES; MEMBRANE-PROTEINS; TRANSPORT-SYSTEM; REDOX CONDITIONS; RNA-SYNTHESIS; ORGANELLES; EVOLUTION; NUCLEUS; IMPORT;
D O I
10.1002/cfg.245
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Chloroplasts and mitochondria originated as bacterial symbionts. The larger, host cells acquired genetic information from their prokaryotic guests by lateral gene transfer. The prokaryotically-derived genes of the eukaryotic cell nucleus now function to encode the great majority of chloroplast and mitochondrial proteins, as well as many proteins of the nucleus and cytosol. Genes are copied and moved between cellular compartments with relative ease, and there is no established obstacle to successful import of any protein precursor from the cytosol. Yet chloroplasts and mitochondria have not abdicated all genes and gene expression to the nucleus and to cytosolic translation. What, then, do chloroplast- and mitochondrially-encoded proteins have in common that confers a selective advantage on the cytoplasmic location of their genes? The proposal advanced here is that co-location of chloroplast and mitochondrial genes with their gene products is required for rapid and direct regulatory coupling. Redox control of gene expression is suggested as the common feature of those chloroplast and mitochondrial proteins that are encoded in situ. Recent evidence is consistent with this hypothesis, and its underlying assumptions and predictions are described. Copyright (C) 2003 John Wiley Sons, Ltd.
引用
收藏
页码:31 / 36
页数:6
相关论文
共 53 条
[11]   The Tat protein export pathway [J].
Berks, BC ;
Sargent, F ;
Palmer, T .
MOLECULAR MICROBIOLOGY, 2000, 35 (02) :260-274
[12]   EVOLUTION OF ORGANELLES AND EUKARYOTIC GENOMES [J].
BOGORAD, L .
SCIENCE, 1975, 188 (4191) :891-898
[13]   LIMITATIONS TO IN-VIVO IMPORT OF HYDROPHOBIC PROTEINS INTO YEAST MITOCHONDRIA - THE CASE OF A CYTOPLASMICALLY SYNTHESIZED APOCYTOCHROME-B [J].
CLAROS, MG ;
PEREA, J ;
SHU, YM ;
SAMATEY, FA ;
POPOT, JL ;
JACQ, C .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1995, 228 (03) :762-771
[14]   Phylogenetic classification and the universal tree [J].
Doolittle, WF .
SCIENCE, 1999, 284 (5423) :2124-2128
[15]   Molecular evolution - A hydrogen-producing mitochondrion [J].
Embley, TM ;
Martin, W .
NATURE, 1998, 396 (6711) :517-519
[16]   The alpha and the beta: protein translocation across mitochondrial and plastid outer membranes [J].
Gabriel, K ;
Buchanan, SK ;
Lithgow, T .
TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (01) :36-40
[17]   Protein synthesis by isolated pea mitochondria is dependent on the activity of respiratory complex II [J].
Galvis, MLE ;
Allen, JF ;
Håkansson, G .
CURRENT GENETICS, 1998, 33 (05) :320-329
[18]  
GATENBY AA, 1990, ANNU REV CELL BIOL, V6, P125
[19]   Evolutionary biology - Mitochondrial genes on the move [J].
Gray, MW .
NATURE, 2000, 408 (6810) :302-305
[20]   Mitochondrial evolution [J].
Gray, MW ;
Burger, G ;
Lang, BF .
SCIENCE, 1999, 283 (5407) :1476-1481