Copper salt-catalyzed azide-[3+2] cycloadditions of ynamides and bis-ynamides

被引：75

作者：

Zhang, Xuejun

Li, Hongyan

You, Lingfeng

Tang, Yu

Hsung, Richard P.

机构：

[1] Univ Wisconsin, Div Pharmaceut Sci, Madison, WI 53705 USA

[2] Univ Wisconsin, Dept Chem, Madison, WI 53705 USA

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2006年 / 348卷 / 16-17期

关键词：

azide-[3+2] cycloaddition; bis-triazoles; bis-ynamides; Cu(I) catalysis; triazoles; ynamides; ONE-POT SYNTHESIS; 1,3-DIPOLAR CYCLOADDITION; CHIRAL YNAMIDES; CLICK-CHEMISTRY; 1.3-DIPOLARE CYCLOADDITIONEN; ALKYNYL BROMIDES; N-ALKYNYLATION; AZIDES; CYCLIZATION; 1,2,3-TRIAZOLES;

D O I：

10.1002/adsc.200600404

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A one-pot synthesis of amide-substituted triazoles from alkyl bromides and ynamides is described here along with syntheses of novel bis-yn-amides and their applications in [3 + 2] cycloadditions with azides to construct unique bis-triazoles.

引用

收藏

页码：2437 / 2442

页数：6

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