Clinical MR-Mammography: Are Computer-Assisted Methods Superior to Visual or Manual Measurements for Curve Type Analysis? A Systematic Approach

被引：36

作者：

Baltzer, Pascal Andreas Thomas ^{[1
,2
]}

Freiberg, Christian ^{[1
,2
]}

Beger, Sebastian ^{[1
,2
]}

Vag, Tibor ^{[1
,2
]}

Dietzel, Matthias ^{[1
,2
]}

Herzog, Aimee B. ^{[1
,2
]}

Gajda, Mieczyslaw ^{[3
]}

Camara, Oumar ^{[4
]}

Kaiser, Werner A. ^{[1
,2
]}

机构：

[1] Univ Jena, Inst Diagnost, D-07740 Jena, Germany

[2] Univ Jena, Inst Intervent Radiol, D-07740 Jena, Germany

[3] Univ Jena, Inst Pathol, D-07740 Jena, Germany

[4] Univ Jena, Clin Gynecol, D-07740 Jena, Germany

来源：

ACADEMIC RADIOLOGY | 2009年 / 16卷 / 09期

关键词：

Computer-aided diagnosis; computer-assisted diagnosis; CAD; breast MRI; dynamic enhancement pattern; kinetics; curve type analysis; sensitivity and specificity; CONTRAST-ENHANCED MRI; POSITIVE PREDICTIVE-VALUE; DETECTED BREAST-LESIONS; MALIGNANT LESIONS; GD-DTPA; QUANTITATIVE ASSESSMENT; DISCRIMINATING BENIGN; DYNAMIC MRI; TUMORS; DIFFERENTIATION;

D O I：

10.1016/j.acra.2009.03.017

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Rationale and Objectives. Enhancement characteristics after administration of a contrast agent are regarded as a major criterion for differential diagnosis in magnetic resonance mammography (MRM). However, no consensus exists about the best measurement method to assess contrast enhancement kinetics. This systematic investigation was performed to compare visual estimation with manual region of interest (ROI) and computer-aided diagnosis (CAD) analysis for time curve measurements in MRM. Materials and Methods. A total of 329 patients undergoing surgery after MRM (1.5 T) were analyzed prospectively. Dynamic data were measured using visual estimation, including ROI as well as CAD methods, and classified depending on initial signal increase and delayed enhancement. Results. Pathology revealed 469 lesions (279 malignant, 190 benign). Kappa agreement between the methods ranged from 0.78 to 0.81. Diagnostic accuracies of 74.4% (visual), 75.7% (ROI), and 76.6% (CAD) were found without statistical significant differences. Conclusions. According to our results, curve type measurements are useful as a diagnostic criterion in breast lesions irrespective of the method used.

引用

页码：1070 / 1076

页数：7

共 30 条

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