Miniaturisation: a well-defined trend in separation and preconcentration techniques

被引:22
作者
deCastro, MDL
GamizGracia, L
机构
[1] Department of Analytical Chemistry, Faculty of Sciences, University of Córdoba
关键词
miniaturisation; separation techniques; overview;
D O I
10.1016/S0003-2670(97)00341-3
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
An overview of the state-of-the-art on miniaturisation concerning the different types of separation techniques is presented. Four groups of these techniques can be distinguished: Chromatographic techniques, including capillary electrophoresis; non-chromatographic continuous separation techniques; discontinuous separation techniques and coupled techniques. The shortcomings encountered in the development of these techniques and the advantages and disadvantages are discussed in this paper. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:23 / 40
页数:18
相关论文
共 105 条
[51]  
KARLBERG B, 1981, ANAL CHIM ACTA, V98, P1
[52]   RAPID NORMAL RAMAN-SPECTROSCOPY OF SUB-PPM OXY-ANION SOLUTIONS - THE ROLE OF ELECTROPHORETIC PRECONCENTRATION [J].
KOWALCHYK, WK ;
WALKER, PA ;
MORRIS, MD .
APPLIED SPECTROSCOPY, 1995, 49 (08) :1183-1188
[54]  
LEE G, 1989, AM LAB FEB, P110
[55]   Microfabrication of a planar absorbance and fluorescence cell for integrated capillary electrophoresis devices [J].
Liang, ZH ;
Chiem, N ;
Ocvirk, G ;
Tang, T ;
Fluri, K ;
Harrison, DJ .
ANALYTICAL CHEMISTRY, 1996, 68 (06) :1040-1046
[56]   PHARMACOKINETIC STUDIES USING MICRODIALYSIS PROBES IN SUBCUTANEOUS TISSUE - EFFECTS OF THE COADMINISTRATION OF ETHANOL AND ACETAMINOPHEN [J].
LINHARES, MC ;
KISSINGER, PT .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1994, 12 (05) :619-627
[57]  
MANZ A, 1993, HRC-J HIGH RES CHROM, V16, P433
[58]   PLANAR CHIPS TECHNOLOGY FOR MINIATURIZATION AND INTEGRATION OF SEPARATION TECHNIQUES INTO MONITORING SYSTEMS - CAPILLARY ELECTROPHORESIS ON A CHIP [J].
MANZ, A ;
HARRISON, DJ ;
VERPOORTE, EMJ ;
FETTINGER, JC ;
PAULUS, A ;
LUDI, H ;
WIDMER, HM .
JOURNAL OF CHROMATOGRAPHY, 1992, 593 (1-2) :253-258
[59]  
MANZ A, 1991, CHIMIA, V45, P103
[60]   DETERMINATION OF TOTAL AND FREE SULFUR-DIOXIDE IN WINE WITH A CONTINUOUS-FLOW MICRODISTILLATION SYSTEM [J].
MAQUIEIRA, A ;
CASAMAYOR, F ;
PUCHADES, R ;
SAGRADO, S .
ANALYTICA CHIMICA ACTA, 1993, 283 (01) :401-407