Antifungal thiosulfonates: Potency with some selectivity

被引：22

作者：

Baerlocher, FJ ^{[1
]}

Baerlocher, MO

Chaulk, CL

Langler, RF

MacQuarrie, SL

机构：

[1] Mt Allison Univ, Dept Biol, Sackville, NB E4L 1G7, Canada

[2] Mt Allison Univ, Dept Chem, Sackville, NB E4L 1G8, Canada

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2000年 / 53卷 / 05期

关键词：

antifungal; fungitoxins; thiosulfonate synthesis; structure-activity;

D O I：

10.1071/CH00030

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of thiosulfonates have been prepared and tested against Aspergillus niger and Aspergillus flavus. In general, the thiosulfonates are moderate antifungal agents-more potent than corresponding inactive disulfides and less potent than corresponding very active fungitoxic disulfides. A pair of thiosulfonates show high selectivity, each killing only one kind of fungus.

引用

页码：399 / 402

页数：4

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