The nucleolus: the magician's hat for cell cycle tricks

被引：131

作者：

Visintin, R ^{[1
]}

Amon, A ^{[1
]}

机构：

[1] MIT, Ctr Canc Res, Cambridge, MA 02139 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2000年 / 12卷 / 03期

关键词：

D O I：

10.1016/S0955-0674(00)00102-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The nucleolus, for decades considered a ribosome factory and site for ribosomal RNA synthesis and processing, has recently acquired new fame. Analyses of proteins important for cell-cycle regulation have shown that this organelle is used to sequester proteins, thereby inhibiting their activity.

引用

页码：372 / 377

页数：6

共 57 条

[1] SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
Bai, C
Sen, P
Hofmann, K
Ma, L
Goebl, M
Harper, JW
Elledge, SJ
[J]. CELL, 1996, 86 (02) : 263 - 274
[2] DMC1 - A MEIOSIS-SPECIFIC YEAST HOMOLOG OF ESCHERICHIA-COLI RECA REQUIRED FOR RECOMBINATION, SYNAPTONEMAL COMPLEX-FORMATION, AND CELL-CYCLE PROGRESSION
BISHOP, DK
PARK, D
XU, LZ
KLECKNER, N
[J]. CELL, 1992, 69 (03) : 439 - 456
[3] Zip2, a meiosis-specific protein required for the initiation of chromosome synapsis
Chua, PR
Roeder, GS
[J]. CELL, 1998, 93 (03) : 349 - 359
[4] Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p
CohenFix, O
Peters, JM
Kirschner, MW
Koshland, D
[J]. GENES & DEVELOPMENT, 1996, 10 (24) : 3081 - 3093
[5] The MDM2 oncoprotein binds specifically to RNA through its RING finger domain
Elenbaas, B
Dobbelstein, M
Roth, J
Shenk, T
Levine, AJ
[J]. MOLECULAR MEDICINE, 1996, 2 (04) : 439 - 451
[6] Cell cycle checkpoints: Preventing an identity crisis
Elledge, SJ
[J]. SCIENCE, 1996, 274 (5293) : 1664 - 1672
[7] A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
Feldman, RMR
Correll, CC
Kaplan, KB
Deshaies, RJ
[J]. CELL, 1997, 91 (02) : 221 - 230
[8] FRANKE WW, 1988, EUR J CELL BIOL, V47, P145
[9] Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6
Freedman, DA
Levine, AJ
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (12) : 7288 - 7293
[10] Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev
Fridell, RA
Fischer, U
Luhrmann, R
Meyer, BE
Meinkoth, JL
Malim, MH
Cullen, BR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (07) : 2936 - 2940

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