Responsive nanoassemblies via interpolyelectrolyte complexation of amphiphilic block copolymer micelles

被引：124

作者：

Lokitz, Brad S.

Convertine, Anthony J.

Ezell, Ryan G.

Heidenreich, Andrew

Li, Yuting

McCormick, Charles L. ^{[1
]}

机构：

[1] Univ So Mississippi, Dept Chem & Biochem, Hattiesburg, MS 39406 USA

[2] Univ So Mississippi, Dept Polymer Sci, Hattiesburg, MS 39406 USA

来源：

MACROMOLECULES | 2006年 / 39卷 / 25期

关键词：

D O I：

10.1021/ma061672y

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Shell "locked" nanoassemblies ranging in size from 34 to 78 nm have been prepared from interpolyelectrolyte complexation of block copolymer micelles of poly[(N,N-dimethylacrylamide)-b-(N-acryloylalanine)-b-(N-isopropylacrylamide)] with the homopolymer poly(ar-vinylbenzyl)trimethylammonium chloride above the unimer to micelle phase transition temperature of the block copolymer in water. Of technological significance is the reversibility of the shell cross-linking by addition of 0.4 M NaCl, allowing micelle dissociation below the lower critical solution temperature of the copolymer micelles. Poly(N-acryloylalanine) (AAL) and block copolymers were prepared directly in water via controlled reversible addition fragmentation chain transfer ( RAFT) polymerization utilizing mono- and difunctional poly(N,N-dimethylacrylamide) macroCTAs.

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页码：8594 / 8602

页数：9

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