Thioglycoligases: Mutant glycosidases for thioglycoside synthesis

被引：123

作者：

Jahn, M

Marles, J

Warren, RAJ

Withers, SG

机构：

[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

[2] Univ British Columbia, Dept Microbiol, Vancouver, BC, Canada

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 03期

关键词：

D O I：

10.1002/anie.200390114

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Engineering of the active site of retaining glycosidases in conjunction with the appropriate modification of their substrates has led to the enzymatic synthesis of thioglycosidic linkages in thiooligosaccharides (see scheme).

引用

页码：352 / +

页数：4

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