The genome of Brucella melitensis

被引:47
作者
DelVecchio, VG [1 ]
Kapatral, V
Elzer, P
Patra, G
Mujer, CV
机构
[1] Univ Scranton, Inst Mol Biol & Med, Scranton, PA 18510 USA
[2] Integrated Genom Inc, Chicago, IL 60612 USA
[3] Louisiana State Univ, AgCtr, Dept Vet Sci, Baton Rouge, LA 70803 USA
关键词
Brucella melitensis; Brucella; genomics;
D O I
10.1016/S0378-1135(02)00238-9
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The genome of Brucella melitensis strain 16M was sequenced and contained 3,294,931 bp distributed over two circular chromosomes. Chromosome I was composed of 2,117,144 bp and chromosome II has 1,177,787 bp. A total of 3198 ORFs were predicted. The origins of replication of the chromosomes are similar to each other and to those of other alpha-proteobacteria. Housekeeping genes such as those that encode for DNA replication, protein synthesis, core metabolism, and cell-wall biosynthesis were found on both chromosomes. Genes encoding adhesins, invasins, and hemolysins were also identified. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:587 / 592
页数:6
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