Neural circuitry of submissive behavior in social anxiety disorder: A preliminary study of response to direct eye gaze

被引:30
作者
Schneier, Franklin R. [1 ,2 ]
Kent, Justine M. [2 ]
Star, Ava [3 ]
Hirsch, Joy [3 ]
机构
[1] New York State Psychiat Inst & Hosp, Anxiety Disorders Clin, New York, NY 10032 USA
[2] Columbia Univ, Coll Phys & Surg, Dept Psychiat, New York, NY USA
[3] Columbia Univ, Dept Radiol, Coll Phys & Surg, Ctr Neurobiol & Behav, New York, NY USA
关键词
fMRI; Brain imaging; Social phobia; PHOBIA; FACES; ACTIVATION;
D O I
10.1016/j.pscychresns.2008.06.004
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Fear of eye gaze is common in social anxiety disorder (SAD) and may represent an evolutionarily conserved submissive behavior. SAD subjects and healthy volunteers who underwent functional magnetic resonance imaging showed significant differences in neural activity in amygdala, fusiform, insula, anterior cingulate and prefrontal cortex in response to direct versus averted gaze. Neural response to direct gaze may identify brain regions important in the pathophysiology of SAD. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:248 / 250
页数:3
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