ATF3 regulates multiple targets and may play a dual role in cardiac hypertrophy and injury

被引：43

作者：

Zhou, Heng ^{[1
,2
]}

Guo, Haipeng ^{[3
,4
]}

Zong, Jing ^{[5
]}

Dai, Jia ^{[1
,2
]}

Yuan, Yuan ^{[1
,2
]}

Bian, Zhou-Yan ^{[1
,2
]}

Tang, Qi-Zhu ^{[1
,2
]}

机构：

[1] Wuhan Univ, Renmin Hosp, Dept Cardiol, Wuhan 430060, Peoples R China

[2] Wuhan Univ, Cardiovasc Res Inst, Wuhan 430060, Peoples R China

[3] Shandong Univ, Qilu Hosp, Key Lab Cardiovasc Remodeling & Funct Res, Chinese Minist Educ, Jinan 250012, Peoples R China

[4] Shandong Univ, Qilu Hosp, Chinese Minist Hlth, Jinan 250012, Peoples R China

[5] Xuzhou Med Coll, Affiliated Hosp, Dept Cardiol, Xuzhou 221000, Peoples R China

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2014年 / 174卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Activating transcription factor 3; Cardiac hypertrophy; Fibrosis; Inflammation;

D O I：

10.1016/j.ijcard.2014.04.160

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

[No abstract available]

引用

页码：838 / +

页数：3

共 12 条

[1]

Feedback regulation by Atf3 in the endothelin-1-responsive transcriptome of cardiomyocytes: Egr1 is a principal Atf3 target [J].

Giraldo, Alejandro ;

Barrett, Oliver P. T. ;

Tindall, Marcus J. ;

Fuller, Stephen J. ;

Amirak, Emre ;

Bhattacharya, Bonhi S. ;

Sugden, Peter H. ;

Clerk, Angela .

BIOCHEMICAL JOURNAL, 2012, 444 :343-355

[2]

The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis [J].

Hai, T ;

Hartman, MG .

GENE, 2001, 273 (01) :1-11

[3]

ATF3, a Hub of the Cellular Adaptive-Response Network, in the Pathogenesis of Diseases: Is Modulation of Inflammation a Unifying Component? [J].

Hai, Tsonwin ;

Wolford, Christopher C. ;

Chang, Yi-Seok .

GENE EXPRESSION, 2010, 15 (01) :1-11

[4]

Angiotensin II signaling up-regulates the immediate early transcription factor ATF3 in the left but not the right atrium [J].

Hasin, Tal ;

Elhanani, Ofer ;

Abassi, Zaid ;

Hai, Tsonwin ;

Aronheim, Ami .

BASIC RESEARCH IN CARDIOLOGY, 2011, 106 (02) :175-187

[5]

Regulation of cardiac hypertrophy by intracellular signalling pathways [J].

Heineke, Joerg ;

Molkentin, Jeffery D. .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2006, 7 (08) :589-600

[6]

Inhibition of basic leucine zipper transcription is a major mediator of atrial dilatation [J].

Kehat, Izhak ;

Heinrich, Ronit ;

Ben-Izhak, Ofer ;

Miyazaki, Hiroshi ;

Gutkind, J. Silvio ;

Aronheim, Ami .

CARDIOVASCULAR RESEARCH, 2006, 70 (03) :543-554

[7]

Molecular Pathways Underlying Cardiac Remodeling During Pathophysiological Stimulation [J].

Kehat, Izhak ;

Molkentin, Jeffery D. .

CIRCULATION, 2010, 122 (25) :2727-2735

[8]

Adult Cardiac Expression of the Activating Transcription Factor 3, ATF3, Promotes Ventricular Hypertrophy [J].

Koren, Lilach ;

Elhanani, Ofer ;

Kehat, Izhak ;

Hai, Tsonwin ;

Aronheim, Ami .

PLOS ONE, 2013, 8 (07)

[9]

ATF3 inhibits doxorubicin-induced apoptosis in cardiac myocytes: A novel cardioprotective role of ATF3 [J].

Nobori, K ;

Ito, H ;

Tamamori-Adachi, M ;

Adachi, S ;

Ono, Y ;

Kawauchi, J ;

Kitajima, S ;

Marumo, F ;

Isobe, M .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2002, 34 (10) :1387-1397

[10]

Transgenic mice with cardiac-specific expression of activating transcription factor 3, a stress-inducible gene, have conduction abnormalities and contractile dysfunction [J].

Okamoto, Y ;

Chaves, A ;

Chen, JC ;

Kelley, R ;

Jones, K ;

Weed, HG ;

Gardner, KL ;

Gangi, L ;

Yamaguchi, M ;

Klomkleaw, W ;

Nakayama, T ;

Hamlin, RL ;

Carnes, C ;

Altschuld, R ;

Bauer, J ;

Hai, T .

AMERICAN JOURNAL OF PATHOLOGY, 2001, 159 (02) :639-650

← 1 2 →