Novel chiral dendritic diphosphine ligands for Rh(I)-catalyzed asymmetric hydrogenation: Remarkable structural effects on catalytic properties

被引：64

作者：

Yi, B ^{[1
]}

Fan, QH

Deng, GJ

Li, YM

Qiu, LQ

Chan, ASC

机构：

[1] Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Biol Chem Lab, Beijing 100080, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai, Peoples R China

[3] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 09期

关键词：

D O I：

10.1021/ol036512a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of dendritic ligands with a chiral diphosphine located at the focal point have been synthesized through coupling of pyrphos 2 with Frechet-type polyether dendron 3. The relationship between the primary structure of the dendrimer and its catalytic properties was established in the Rh-catalyzed asymmetric hydrogenation of alpha-acetamido cinnamic acid 4. A remarkable structural effect on catalytic activity was observed.

引用

页码：1361 / 1364

页数：4

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