Recent advances (1995-2005) in fluorinated pharmaceuticals based on natural products

被引：587

作者：

Begue, Jean-Pierre ^{[1
]}

Bonnet-Delpon, Daniele ^{[1
]}

机构：

[1] Fac Pharm Chatenay Malabry, BIOCIS, UMR 8076, F-92296 Chatenay Malabry, France

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2006年 / 127卷 / 08期

关键词：

fluorinated compounds; fluoro substituent; pharmaceuticals; anti-cancer agents; natural products; drugs; anti-parasitic agents; fluorosteroids;

D O I：

10.1016/j.jfluchem.2006.05.006

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This present report is devoted to the recent advances, in these last 10 years, in fluorinated analogues of natural products developed as pharmaceuticals, marketed, registered or in clinical development. These mainly concern fluorine-substituted nucleosides, alkaloids, macrolides, steroids, amino acids and prostaglandins. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：992 / 1012

页数：21

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