Effect of Electroanatomically Guided Versus Conventional Catheter Ablation of Typical Atrial Flutter on the Fluoroscopy Time and Resource Use: A Prospective Randomized Multicenter Study

被引:55
作者
Hindricks, Gerhard [1 ]
Willems, Stefan [2 ]
Kautzner, Josef [3 ]
De Chillou, Christian [4 ]
Wiedemann, Michael [5 ]
Schepel, Siep [6 ]
Piorkowski, Christopher
Risius, Tim [2 ]
Kottkamp, Hans [7 ]
机构
[1] Univ Leipzig, Ctr Heart, Dept Electrophysiol, D-04289 Leipzig, Germany
[2] Univ Hosp Eppendorf, Hamburg, Germany
[3] IKEM, Inst Clin & Expt Med, Prague, Czech Republic
[4] Univ Nancy, CHU Brabois, Vandoeuvre Les Nancy, France
[5] Am Urban Hosp, Berlin, Germany
[6] Biosense Webster EMEA, Waterloo, Belgium
[7] Clin Ctr Hirslanden, Zurich, Switzerland
关键词
atrial flutter; electroanatomical mapping; radiofrequency catheter ablation; fluoroscopy time; VENTRICULAR-TACHYCARDIA; RADIOFREQUENCY ABLATION; TIP; ISTHMUS; SAFETY;
D O I
10.1111/j.1540-8167.2009.01439.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims: Radiofrequency catheter ablation of typical atrial flutter is one of the most frequent indications for catheter ablation in electrophysiology laboratories today. Clinical utility of electroanatomic mapping systems on treatment results and resource utilization compared with conventional ablation has not been systematically investigated in a prospective multicenter study. Methods and Results: In this prospective, randomized multicenter study, the results of catheter ablation to cure typical atrial flutter using conventional ablation strategy were compared with electroanatomically guided mapping and ablation (Carto (R)). Primary endpoints of the study were procedure duration and fluoroscopy exposure time, secondary endpoints were acute success rate, recurrence rate, and resource utilization. A total of 210 patients (169 men, 41 women, mean age 63 +/- 10 years) with documented typical atrial flutter were included in the study. Acute ablation success, that is, demonstration of bidirectional isthmus block, was achieved in 99 of 105 patients (94%) in the electroanatomically guided ablation group and in 102 of 105 patients (97%) in the conventional ablation group (P > 0.05). Total procedure duration was comparable between both study groups (99 +/- 57 minutes vs 88 +/- 54 minutes, P > 0.05). Fluoroscopy exposure time was significantly shorter in the electroanatomically guided ablation group (7.7 +/- 7.3 minutes vs 14.8 +/- 11.9 minutes; P < 0.05). Total recurrence rate of typical atrial flutter at 6 months of follow-up was comparable between the 2 groups (respectively for the CARTO and conventional group 6.6% vs 5.7%, P > 0.05). The material costs per procedure in the electroanatomically guided and conventional groups (NaviStar (R) DS vs Celsius (R) DS) was euro3035 (USD 3,870) and euro2133 (USD 2,720), respectively. Conclusions: This multicenter study documented that cavotricuspid isthmus ablation to cure typical atrial flutter was highly effective and safe, both in the conventional and the electroanatomically guided ablation group. The use of electroanatomical mapping system significantly reduced the fluoroscopy exposure time by almost 50%, however, at the expense of increased cost of the procedure. (J Cardiovasc Electrophysiol, Vol. 20, pp. 734-740, July 2009).
引用
收藏
页码:734 / 740
页数:7
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