Synthesis and post-synthetic derivatization of a cyanine-based amino acid.: Application to the preparation of a novel water-soluble NIR dye

被引：30

作者：

Chipon, Bertrand

Clave, Guillaume

Bouteiller, Cedric

Massonneau, Marc

Renard, Pierre-Yves ^{[1
]}

Romieu, Anthony

机构：

[1] INSA Rouen, UMR 6014, CNRS, IRCOF,LHO,Equipe Chim Bioorgan, F-76131 Mont St Aignan, France

[2] Univ Rouen, F-76131 Mont St Aignan, France

[3] ESIGELEC, QUIDD, F-76801 St Etienne, France

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 47期

关键词：

cyanine dye; fluorescent amino acid; sulfonation;

D O I：

10.1016/j.tetlet.2006.09.100

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of a new fluorescent amino acid derived from a pentamethylene cyanine dye is described. Selective derivatization of its amino group with an original trisulfonated linker has led to a novel water-soluble NIR dye suitable for covalent labeling of biomolecules. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：8279 / 8284

页数：6

共 37 条

[31] Tuning the photoinduced electron transfer in near-infrared heptamethine cyanine dyes [J].