New insecticidal rocaglamide derivatives from flowers of Aglaia duperreana (Meliaceae)

被引：31

作者：

Chaidir

Hiort, J

Nugroho, BW

Bohnenstengel, FI

Wray, V

Witte, L

Hung, PD

Kiet, LC

Sumaryono, W

Proksch, P

机构：

[1] Univ Wurzburg, Lehrstuhl Pharmazeut Biol, Julius von Sachs Inst Biowissensch, D-97082 Wurzburg, Germany

[2] Gesell Biotechnol Forsch mbH, D-38124 Braunschweig, Germany

[3] Tech Univ Carolo Wilhelmina Braunschweig, Inst Pharmazeut Biol, D-38106 Braunschweig, Germany

[4] Vietnam Natl Univ, Coll Nat Sci, Dept Chem, Ho Chi Minh City, Vietnam

[5] Vietnam Natl Univ, Coll Nat Sci, Dept Bot, Ho Chi Minh City, Vietnam

[6] BPPT, Jakarta, Indonesia

[7] Bogor Agr Univ, Fac Agr, Dept Plant Pests & Dis, Bogor 16144, Indonesia

来源：

PHYTOCHEMISTRY | 1999年 / 52卷 / 05期

关键词：

Aglaia duperreana; Meliaceae; benzofurans; rocaglamide derivatives; structure elucidation; natural insecticides; Spodoptera littoralis;

D O I：

10.1016/S0031-9422(99)00327-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Flowers of Aglaia duperreana collected in Vietnam yielded thirteen insecticidal cyclopentatetrahydrobenzofuran derivatives of the rocaglamide type including five compounds which proved to be new natural products. Structure elucidation of the new compounds and their insecticidal activity against larvae of the pest insect Spodoptera littoralis are described. Most of the isolated rocaglamide derivatives exhibited strong to moderate insecticidal activity. The most active compounds were similar with regard to their bioactivity to the well known natural insecticide azadirachtin, However, replacement of the OH-group at C-8b (that is a characteristic structural feature of most known rocaglamide congeners) by an OC2H5-substituent as present in two of the isolated new derivatives was found to result in a loss of insecticidal activity. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：837 / 842

页数：6

共 11 条

[1] New nitrogenous and aromatic derivatives from Aglaia argentea and A-forbesii [J].