probeBase - an online resource for rRNA-targeted oligonucleotide probes: new features 2007

被引:375
作者
Loy, Alexander [1 ]
Maixner, Frank [1 ]
Wagner, Michael [1 ]
Horn, Matthias [1 ]
机构
[1] Univ Vienna, Dept Mikrobioelle Okol, A-1090 Vienna, Austria
基金
奥地利科学基金会;
关键词
D O I
10.1093/nar/gkl856
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
probeBase is a curated database of annotated rRNA-targeted oligonucleotide probes and supporting information. Rapid access to probe, microarray and reference data is achieved by powerful search tools and via different lists that are based on selected categories such as functional or taxonomic properties of the target organism(s) or the hybridization format (fluorescence in situ hybridization or microarray) in which the probes were applied. Additional information on probe coverage and specificity is available through direct submissions of probe sequences from probeBase to RDP-II and Green-genes, two major rRNA sequence databases. A freely editable user comments field for each probe entry allows any user to add, modify or remove information or to report errors in real-time. probeBase entries increased from 700 to more than 1200 during the past three years. Several options for submission of single probes or entire probe sets, even prior to publication of newly developed probes, should further contribute to keeping probeBase an up-to-date and useful resource. probeBase is freely accessible at http://www.microbial-ecology.net/probebase.
引用
收藏
页码:D800 / D804
页数:5
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