The BAR Domain Superfamily: Membrane-Molding Macromolecules

被引:447
作者
Frost, Adam [1 ,4 ,5 ]
Unger, Vinzenz M. [1 ,4 ]
De Camilli, Pietro [2 ,3 ,4 ,5 ,6 ,7 ]
机构
[1] Yale Univ, Sch Med, Dept Mol Biophys & Biochem, New Haven, CT 06510 USA
[2] Yale Univ, Sch Med, Dept Cell Biol, New Haven, CT 06510 USA
[3] Yale Univ, Sch Med, Dept Neurobiol, New Haven, CT 06510 USA
[4] Yale Univ, Sch Med, Interdepartmental Neurosci Program, New Haven, CT 06510 USA
[5] Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06510 USA
[6] Yale Univ, Sch Med, Kavli Inst Neurosci, New Haven, CT 06510 USA
[7] Yale Univ, Sch Med, Program Cellular Neurosci Neurodegenerat & Repair, New Haven, CT 06510 USA
关键词
SYNAPTIC VESICLE ENDOCYTOSIS; MEDIATED ENDOCYTOSIS; ACTIN CYTOSKELETON; AMPHIPHYSIN-2; BIN1; STRUCTURAL BASIS; FISSION YEAST; PROTEINS; CURVATURE; FAMILY; INVAGINATION;
D O I
10.1016/j.cell.2009.04.010
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Membrane-shaping proteins of the BAR domain superfamily are determinants of organelle biogenesis, membrane trafficking, cell division, and cell migration. An upsurge of research now reveals new principles of BAR domain-mediated membrane remodeling, enhancing our understanding of membrane curvature-mediated information processing.
引用
收藏
页码:191 / 196
页数:6
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