Lipase-Catalyzed Ring-Opening Polymerization of the O-Carboxylic Anhydride Derived from Lactic Acid

被引：42

作者：

Bonduelle, Colin

Martin-Vaca, Blanca

Bourissou, Didier ^{[1
]}

机构：

[1] Univ Toulouse, UPS, LHFA, F-31062 Toulouse, France

来源：

BIOMACROMOLECULES | 2009年 / 10卷 / 11期

关键词：

SYNTHETIC BIODEGRADABLE POLYMERS; ORGANIC MEDIA; ENZYMATIC POLYMERIZATION; CHEMOENZYMATIC SYNTHESIS; CYCLIC ESTERS; POLYESTERS; COPOLYMERIZATION; LACTONES; POLYLACTIDE;

D O I：

10.1021/bm9007343

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Both lipase PS and Novozym 435 promote the ring-opening polymerization of lacOCA, the O-carboxylic anhydride derived from lactic acid. Accordingly, PLA of relatively high molecular weights (M-n up to 38400 g/mol) and low polydispersities (M-w/M-n < 1.4) are obtained in high yields within a few hours at 80 degrees C. Slight preference for L-lacOCA over D-lacOCA is observed, and with Novozym 435, the molecular weight of the obtained PLA can be controlled by varying the lipase loading.

引用

页码：3069 / 3073

页数：5

共 65 条

[61] Complexes of Mg, Ca and Zn as homogeneous catalysts for lactide polymerization [J].