Mild and highly selective formyl protection of primary hydroxyl groups

被引：43

作者：

De Luca, L ^{[1
]}

Giacomelli, G ^{[1
]}

Porcheddu, A ^{[1
]}

机构：

[1] Univ Sassari, Dipartimento Chim, I-07100 Sassari, Italy

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 15期

关键词：

D O I：

10.1021/jo0257492

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient conversion of primary alcohols to the corresponding formate esters can be carried out at room temperature in methylene chloride, using 2,4,6-trichloro-1,3,5-triazine and N,N-dimethylformamide in the presence of lithium fluoride. This procedure appears as a valid method for selectively protecting primary hydroxyl groups.

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收藏

页码：5152 / 5155

页数：4

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