Molecular complexity of vertebrate tight junctions (Review)

被引：91

作者：

D'Atri, F

Citi, S

机构：

[1] Univ Geneva, Dept Mol Biol, CH-1211 Geneva 4, Switzerland

[2] Univ Geneva, Dept Biochem, CH-1211 Geneva, Switzerland

[3] Univ Padua, Dept Biol, Padua, Italy

来源：

MOLECULAR MEMBRANE BIOLOGY | 2002年 / 19卷 / 02期

关键词：

epithelia; endothelia; polarity; tight junction; protein;

D O I：

10.1080/09687680210129236

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Separation of distinct body, organ and tissue compartments, and maintenance of epithelial cell polarity require tight junctions (TJ)-cell-cell junctions located in the apicolateral regions of epithelial and endothelial cells. Studies on the protein components of vertebrate TJ have revealed an intricate network of membrane, sub-membrane, cytoskeletal, and signalling molecules. How these molecules functionally interact to provide TJ with their functions, and what roles these molecules play in control of cell growth and differentiation is a fundamental problem in cell biology.

引用

页码：103 / 112

页数：10

共 113 条

[41] Link of the unique oncogenic properties of adenovirus type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2
Glaunsinger, BA
Weiss, RS
Lee, SS
Javier, R
[J]. EMBO JOURNAL, 2001, 20 (20) : 5578 - 5586
[42] The junction-associated protein, zonula occludens-1, localizes to the nucleus before the maturation and during the remodeling of cell-cell contacts
Gottardi, CJ
Arpin, M
Fanning, AS
Louvard, D
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (20) : 10779 - 10784
[43] CNS myelin and Sertoli cell tight junction strands are absent in Osp/Claudin-11 null mice
Gow, A
Southwood, CM
Li, JS
Pariali, M
Riordan, GP
Brodie, SE
Danias, J
Bronstein, JM
Kachar, B
Lazzarini, RA
[J]. CELL, 1999, 99 (06) : 649 - 659
[44] Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells
Grindstaff, KK
Yeaman, C
Anandasabapathy, N
Hsu, SC
Rodriguez-Boulan, E
Scheller, RH
Nelson, WJ
[J]. CELL, 1998, 93 (05) : 731 - 740
[45] IDENTIFICATION OF A 160-KDA POLYPEPTIDE THAT BINDS TO THE TIGHT JUNCTION PROTEIN-ZO-1
GUMBINER, B
LOWENKOPF, T
APATIRA, D
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (08) : 3460 - 3464
[46] HAMAZAKI Y, 2001, J BIOL CHEM, V31, P31
[47] ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin
Haskins, J
Gu, LJ
Wittchen, ES
Hibbard, J
Stevenson, BR
[J]. JOURNAL OF CELL BIOLOGY, 1998, 141 (01) : 199 - 208
[48] Hung TJ, 1999, DEVELOPMENT, V126, P127
[49] Localization of membrane-associated guanylate kinase (MAGI)-1/BAI-associated protein (BAP) 1 at tight junctions of epithelial cells
Ide, N
Hata, Y
Nishioka, H
Hirao, K
Yao, I
Deguchi, M
Mizoguchi, A
Nishimori, H
Tokino, T
Nakamura, Y
Takai, Y
[J]. ONCOGENE, 1999, 18 (54) : 7810 - 7815
[50] Afadin: A key molecule essential for structural organization of cell-cell junctions of polarized epithelia during embryogenesis
Ikeda, W
Nakanishi, H
Miyoshi, J
Mandai, K
Ishizaki, H
Tanaka, M
Togawa, A
Takahashi, K
Nishioka, H
Yoshida, H
Mizoguchi, A
Nishikawa, S
Takai, Y
[J]. JOURNAL OF CELL BIOLOGY, 1999, 146 (05) : 1117 - 1131

← 1 2 3 4 5 6 7 8 9 10 →