Sex Matters for Mechanism

被引:33
作者
Danska, Jayne S. [1 ,2 ,3 ]
机构
[1] Hosp Sick Children, Program Genet & Genome Biol, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Dept Immunol, Toronto, ON, Canada
[3] Univ Toronto, Dept Med Biophys, Toronto, ON, Canada
关键词
D O I
10.1126/scitranslmed.3009859
中图分类号
Q2 [细胞生物学];
学科分类号
071013 [干细胞生物学];
摘要
Some funding agencies now require consideration of sex and gender in preclinical research, a policy that heralds opportunities and challenges for researchers.
引用
收藏
页数:3
相关论文
共 10 条
[1]
Prenatal Stress-Induced Increases in Placental Inflammation and Offspring Hyperactivity Are Male-Specific and Ameliorated by Maternal Antiinflammatory Treatment [J].
Bronson, Stefanie L. ;
Bale, Tracy L. .
ENDOCRINOLOGY, 2014, 155 (07) :2635-2646
[2]
NIH to balance sex in cell and animal studies [J].
Clayton, Janine A. ;
Collins, Francis S. .
NATURE, 2014, 509 (7500) :282-283
[3]
Does a Change in Health Research Funding Policy Related to the Integration of Sex and Gender Have an Impact? [J].
Johnson, Joy ;
Sharman, Zena ;
Vissandjee, Bilkis ;
Stewart, Donna E. .
PLOS ONE, 2014, 9 (06)
[4]
SeXX matters in immunity [J].
Markle, J. G. ;
Fish, E. N. .
TRENDS IN IMMUNOLOGY, 2014, 35 (03) :97-104
[5]
Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity [J].
Markle, Janet G. M. ;
Frank, Daniel N. ;
Mortin-Toth, Steven ;
Robertson, Charles E. ;
Feazel, Leah M. ;
Rolle-Kampczyk, Ulrike ;
von Bergen, Martin ;
McCoy, Kathy D. ;
Macpherson, Andrew J. ;
Danska, Jayne S. .
SCIENCE, 2013, 339 (6123) :1084-1088
[6]
Sex-specific genetic architecture of human disease [J].
Ober, Carole ;
Loisel, Dagan A. ;
Gilad, Yoav .
NATURE REVIEWS GENETICS, 2008, 9 (12) :911-922
[7]
Female mice liberated for inclusion in neuroscience and biomedical research [J].
Prendergast, Brian J. ;
Onishi, Kenneth G. ;
Zucker, Irving .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2014, 40 :1-5
[8]
Sexual dimorphism in mammalian gene expression [J].
Rinn, JL ;
Snyder, M .
TRENDS IN GENETICS, 2005, 21 (05) :298-305
[9]
Sex-related differences in pharmacokinetics and pharmacodynamics of anti-hypertensive drugs [J].
Ueno, Koichi ;
Sato, Hiromi .
HYPERTENSION RESEARCH, 2012, 35 (03) :245-250
[10]
Peroxisome proliferator-activated receptor (PPAR)α and -γ regulate IFNγ and IL-17A production by human T cells in a sex-specific way [J].
Zhang, Monan Angela ;
Rego, Dorothy ;
Moshkova, Marina ;
Kebir, Hania ;
Chruscinski, Andrzej ;
HoangKim Nguyen ;
Akkermann, Rainer ;
Stanczyk, Frank Z. ;
Prat, Alexandre ;
Steinman, Lawrence ;
Dunn, Shannon E. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (24) :9505-9510