New method to prepare very stable and biocompatible fluorescent silica nanoparticles

被引：92

作者：

Ha, Shin-Woo ^{[1
]}

Camalier, Corinne E. ^{[2
]}

Beck, George R., Jr. ^{[2
]}

Lee, Jin-Kyu ^{[1
]}

机构：

[1] Seoul Natl Univ, Dept Chem, Seoul, South Korea

[2] Emory Univ, Sch Med, Div Endocrinol Metab & Lipids, Atlanta, GA USA

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 20期

关键词：

DELIVERY; SPHERES; TOXICITY; CARRIERS; DRUG;

D O I：

10.1039/b902195g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new synthetic method has been developed to prepare fluorescent silica nanoparticles without employing isothiocyanated dye molecules and (3-aminopropyl)triethoxysilane (APS) for the thiourea linkage formation; the resulting fluorescent silica nanoparticles show excellent photochemical, thermal and pH stabilities and a good biocompatibility with over 85% viability from various cell types.

引用

收藏

页码：2881 / 2883

页数：3

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