Icosahedral DNA Nanocapsules by Modular Assembly

被引：182

作者：

Bhatia, Dhiraj ^{[1
]}

Mehtab, Shabana ^{[1
]}

Krishnan, Ramya ^{[1
]}

Indi, Shantinath S. ^{[2
]}

Basu, Atanu ^{[3
]}

Krishnan, Yamuna ^{[1
]}

机构：

[1] Natl Ctr Biol Sci, TIRR, GKVK, Bangalore 560065, Karnataka, India

[2] Indian Inst Sci, Dept Microbiol & Cell Biol, Bangalore 560012, Karnataka, India

[3] Natl Inst Virol, Pune 411001, Maharashtra, India

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 23期

关键词：

DNA; five-way junctions; nanotechnology; platonic solids; self-assembly; CONSTRUCTION; LIGATION; MOLECULE;

D O I：

10.1002/anie.200806000

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

It's a trap! DNA polyhedra formed through molecular selfassembly may function as nanocapsules for the targeted delivery of encapsulated entities. This functional aspect was demonstrated for the most complex DNA-based platonic solid: During the stepwise amalgamation of discrete polyhedra to form icosahedra, gold nanoparticles (GNPs) were encapsulated from solution (see illustration and TEM image of icosahedral cages containing GNPs). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：4134 / 4137

页数：4

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