Syntheses and bioactivities of novel carbamates combining platelet activating factor (PAF) receptor antagonist with thromboxane synthase inhibitor (TxSI)

被引:11
作者
Fujita, M
Seki, T
机构
[1] Omiya Research Laboratory, Nikken Chemicals Co., Ltd., Saitama-shi, Saitama 330-0835, 1-346, Kitabukuro-cho
关键词
D O I
10.1016/S0960-894X(02)00186-5
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Synthesis of carbarnates 3b which possess dual-acting PAF antagonist/TxSI using unstable esters 1, diazepines 2, K2CO3 and 18-crown-6 is described. (C) 2002 Published by Elsevier Science Ltd.
引用
收藏
页码:1383 / 1386
页数:4
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