Hashimoto's encephalopathy in the elderly: Relationship to cognitive impairment

被引:22
作者
Galluzzi, S
Geroldi, C
Zanetti, O
Frisoni, GB
机构
[1] IRCCS San Giovanni Dio FBF, Lab Epidemiol & Neuroimaging, I-25125 Brescia, Italy
[2] IRCCS San Giovanni Dio FBF, Alzheimers Unit, I-25125 Brescia, Italy
关键词
D O I
10.1177/089198870201500309
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Hashimoto's encephalopathy (HE) is a steroid-responsive encephalopathy associated with high titers of antithyroid antibodies. To date, 57 pediatric-, adult-, and elderly-onset cases have been described in the literature. The clinical picture is pleomorphic, and cognitive impairment is a frequently reported symptom. We report the case of a patient with slowly progressive cognitive impairment possibly caused by HE. The issue of the differential diagnosis with primary dementia is discussed. A review of cases of HE showing cognitive deterioration is also presented, and factors possibly related to characteristics of cognitive impairment and outcome after therapy are considered.
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收藏
页码:175 / 179
页数:5
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