Coronaviruses: Important Emerging Human Pathogens

被引:137
作者
Coleman, Christopher M. [1 ]
Frieman, Matthew B. [1 ]
机构
[1] Univ Maryland, Sch Med, Dept Microbiol & Immunol, Baltimore, MD 21201 USA
关键词
RESPIRATORY SYNDROME CORONAVIRUS; SARS-CORONAVIRUS; MOLECULAR EVOLUTION; DROMEDARY CAMELS; ANTIBODIES; RECEPTOR; CIVETS; VIRUS; CHINA;
D O I
10.1128/JVI.03488-13
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The identification of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 reaffirmed the importance of understanding how coronaviruses emerge, infect, and cause disease. By comparing what is known about severe acute respiratory syndrome coronavirus (SARS-CoV) to what has recently been found for MERS-CoV, researchers are discovering similarities and differences that may be important for pathogenesis. Here we discuss what is known about each virus and what gaps remain in our understanding, especially concerning MERS-CoV.
引用
收藏
页码:5209 / 5212
页数:4
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