Preparation of chitosan nanofiber tube by electrospinning

被引:36
作者
Matsuda, Atsushi [1 ]
Kagata, Go
Kino, Rikako
Tanaka, Junzo
机构
[1] Hokkaido Univ, Creat Res Initiat Sousei, Sapporo, Hokkaido 0010021, Japan
[2] Tokyo Inst Technol, Dept Met & Ceram Sci, Meguro Ku, Tokyo 1528550, Japan
关键词
electrospinning; water-insoluble treatment; chitosan nanofiber; coating chitosan-cast film; crab-tendon chitosan; nerve-regenerative guide tube;
D O I
10.1166/jnn.2007.520
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Water-insoluble chitosan nanofiber sheets and tubes coated with chitosan-cast film were prepared by electrospinning. When as-spun chitosan nanofiber sheets and tubes were immersed in 28% ammonium aqueous solution, they became insoluble in water and showed nanofiber structures confirmed by SEM micrography. Mechanical properties of chitosan nanofiber sheets and tubes were improved by coating with chitosan-cast film, which gave them a compressive strength higher than that of crab-tendon chitosan, demonstrating that chitosan nanofiber tubes coated with chitosan-cast film are usable as nerve-regenerative guide tubes.
引用
收藏
页码:852 / 855
页数:4
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