Heterogeneous nucleation in and out of pores

被引：217

作者：

Page, Amanda J. ^{[1
]}

Sear, Richard P. ^{[1
]}

机构：

[1] Univ Surrey, Dept Phys, Guildford GU2 7XH, Surrey, England

来源：

PHYSICAL REVIEW LETTERS | 2006年 / 97卷 / 06期

关键词：

D O I：

10.1103/PhysRevLett.97.065701

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We study the nucleation of a new thermodynamic phase in pores and find that the nucleation often proceeds via two steps: nucleation of pore filling, and nucleation out of the pore. These two rates have opposing dependencies on pore size, resulting in a pore size at which the nucleation rate of the new phase is maximal. This finding is relevant to attempts to design and use porous media to crystallize proteins.

引用

页数：4

共 18 条

[1] Sampling rare switching events in biochemical networks [J].

Allen, RJ ;

Warren, PB ;

ten Wolde, PR .

PHYSICAL REVIEW LETTERS, 2005, 94 (01)

[2] Forward flux sampling-type schemes for simulating rare events: Efficiency analysis [J].

Allen, Rosalind J. ;

Frenkel, Daan ;

ten Wolde, Pieter Rein .

JOURNAL OF CHEMICAL PHYSICS, 2006, 124 (19)

[3]

[Anonymous], 2021, METASTABLE LIQUIDS

[4]

[Anonymous], 1987, Introduction to Modern Statistical Mechanics

[5] Experiment and theory for heterogeneous nucleation of protein crystals in a porous medium [J].

Chayen, NE ;

Saridakis, E ;

Sear, RP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (03) :597-601

[6] Is lysozyme really the ideal model protein? [J].

Chayen, NE ;

Saridakis, E .

JOURNAL OF CRYSTAL GROWTH, 2001, 232 (1-4) :262-264

[7] Porous silicon: an effective nucleation-inducing material for protein crystallization [J].

Chayen, NE ;

Saridakis, E ;

El-Bahar, R ;

Nemirovsky, Y .

JOURNAL OF MOLECULAR BIOLOGY, 2001, 312 (04) :591-595

[8] Metastability in the two-dimensional Ising model with free boundary conditions [J].

Cirillo, ENM ;

Lebowitz, JL .

JOURNAL OF STATISTICAL PHYSICS, 1998, 90 (1-2) :211-226

[9] Phase separation in confined systems [J].

Gelb, LD ;

Gubbins, KE ;

Radhakrishnan, R ;

Sliwinska-Bartkowiak, M .

REPORTS ON PROGRESS IN PHYSICS, 1999, 62 (12) :1573-1659

[10] Nucleation in cylindrical capillaries [J].

Husowitz, B ;

Talanquer, V .

JOURNAL OF CHEMICAL PHYSICS, 2004, 121 (16) :8021-8028

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