Advantages of structural similarities of the reactants in optical resolution processes

被引：3

作者：

Faigl, Ferenc

Schindler, Jozsef

Fogassy, Elemer

机构：

[1] Budapest Univ Technol & Econ, Hungarian Acad Sci, Res Grp, H-1111 Budapest, Hungary

[2] Budapest Univ Technol & Econ, Hungarian Acad Sci, Dept Organ Chem Technol, H-1111 Budapest, Hungary

来源：

NOVEL OPTICAL RESOLUTION TECHNOLOGIES | 2007年 / 269卷

关键词：

optical resolution; diastereoisomeric salt; derivative resolving agent; structural similarity; homo- and heterochiral assemblies;

D O I：

10.1007/128_2006_076

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Advantages and limitations of the use of structurally similar compounds in racemate resolution via diastereoisomeric salt formation are discussed in this review. An effective conception on "derivative resolving agents" (use of the optically active derivatives of a racemate as resolving agents) is presented by examples and the method is extended to the homologous series of the derivative resolving agents and/or achiral additives. A recently developed distillation version of the family approach to optical resolution and the novel, solvent-free resolution methods using a half equivalent amount of resolving agent are also discussed.

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收藏

页码：133 / 157

页数：25

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