Enzyme-responsive materials: a new class of smart biomaterials

被引：337

作者：

Ulijn, Rein V. ^{[1
]}

机构：

[1] Sch Mat & Manchester Interdisciplinary Bioctr, Manchester M1 7HS, Lancs, England

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2006年 / 16卷 / 23期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1039/b601776m

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Enzyme-responsive materials (ERMs) are a new class of smart materials that undergo macroscopic transitions when triggered by selective catalytic actions of enzymes. The use of enzymes as stimuli to trigger mechanical responses in materials opens up a number of possible applications in biology and medicine. Three different classes of ERMs are described, based on supramolecular assemblies, chemically crosslinked gels and (nanoparticle) surfaces. Potential applications in regenerative medicine, diagnostics, and drug delivery are discussed.

引用

页码：2217 / 2225

页数：9

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