Colocalization of GABA(A) and NMDA receptors within the dorsal motor nucleus of the vagus nerve (DMV) of the rat

被引：27

作者：

Broussard, DL

Li, H

Altschuler, SM

机构：

[1] Div. of Gastroenterol. and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA 19104

来源：

BRAIN RESEARCH | 1997年 / 763卷 / 01期

关键词：

GABA(A) receptor; NMDA receptor; pseudorabies virus; immunofluorescence; confocal laser microscopy; dorsal motor nucleus of the vagus nerve; rat;

D O I：

10.1016/S0006-8993(97)00344-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Changes in gastric motor activity are observed in response to glutamate and GABA in the DMV. We investigated the expression of GABA(A) and NMDA receptors within DMV neurons projecting to the stomach using pseudorabies virus (PRV). PRV immunoreactive (PRV-IR) cells expressing GABA(A) alpha 1-IR, also expressed NMDAR1 suggesting that NMDA and GABA(A) receptors are colocalized. These results provide a neuroanatomical basis for these receptors jointly playing a role in gastric motor functions. (C) 1997 Elsevier Science B.V.

引用

页码：123 / 126

页数：4

共 19 条

[1] REPRESENTATION OF THE CECUM IN THE LATERAL DORSAL MOTOR NUCLEUS OF THE VAGUS NERVE AND COMMISSURAL SUBNUCLEUS OF THE NUCLEUS-TRACTUS-SOLITARII IN RAT [J].