Highly selective coupling of alkenes and aldehydes catalyzed by [Ni(NHC){P(OPh)3}]:: Synergy between a strong σ donor and a strong π acceptor

被引：103

作者：

Ho, Chun-Yu ^{[1
]}

Jamison, Timothy F. ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 05期

关键词：

D O I：

10.1002/anie.200603907

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Give and take: Both a strong electron donor (1) and a strong electron acceptor (P(OPh)3) are necessary for a highly selective, nickel-catalyzed coupling reaction between alkenes, aldehydes, and silyl triflates (see scheme; cod = cycloocta-1,5-diene, Tf=trifluoromethanesulfonyl). This synergistic effect may also be useful in other transformations catalyzed by NHC-metal complexes (NHC = N-heterocyclic carbene). © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：782 / 785

页数：4

共 45 条

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