Oral involvement in chronic graft-versus-host disease after allogeneic bone marrow transplantation

被引：53

作者：

Nakamura, S

Hiroki, A

Shinohara, M

Gondo, H

Ohyama, Y

Mouri, T

Sasaki, M

Shirasuna, K

Harada, M

Niho, Y

机构：

[1] KYUSHU UNIV,FAC MED,DEPT INTERNAL MED 1,FUKUOKA 812,JAPAN

[2] OKAYAMA UNIV,FAC MED,DEPT INTERNAL MED 2,OKAYAMA 700,JAPAN

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS | 1996年 / 82卷 / 05期

关键词：

D O I：

10.1016/S1079-2104(96)80203-4

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

We examined 37 patients who had undergone an allogeneic bone marrow transplantation and compared their oral findings to their systemic involvement with chronic graft-versus-host disease. Among the clinical signs and symptoms in their oral region, only the presence of oral lichenoid lesions had a statistically significant relationship to the diagnosis of chronic graft-versus-host disease. The histologic findings in the labial salivary glands and buccal mucosa closely reflected the status of chronic graft-versus-host disease. Statistically, the presence of diffuse and periductal lymphocytic infiltration in labial salivary glands, subepithelial lymphocytic infiltration and epithelial changes in buccal mucosa also showed a significant relationship to the diagnosis of chronic graft-versus-host disease. The present study suggests that a systematic oral examination, especially pathologic examination of the labial salivary glands and buccal mucosa, is useful in evaluating the status of chronic graft-versus-host disease.

引用

页码：556 / 563

页数：8

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