Prolonged electroencephalogram monitoring for seizures and their treatment

被引:40
作者
Clancy, Robert R. [1 ]
机构
[1] Univ Penn, Sch Med, Childrens Hosp Philadelphia, Philadelphia, PA 19104 USA
关键词
D O I
10.1016/j.clp.2006.06.004
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Examining cerebral cortical function in an awake, cooperative adult is a reasonably easy, straightforward task. Cognitive function can be reliably determined by the assessment of orientation, receptive and expressive language, memory, problem solving, mathematical skills, and proverb interpretation. These traditional cognitive tasks are sensitive measures of the integrity of cerebral cortical functioning. In contrast, the same task is daunting in even the healthiest newborn infants. Even in an awake, well newborn infant, no reliable bedside clinical tools demonstrate the health of the cerebral cortex. Because the electroencephalogram (EEG) is exclusively generated by the outermost layers of the cerebral cortex, careful examination of the integrity of the EEG is a sensitive, albeit nonspecific yardstick for measuring the health of the cortex of the immature central nervous system [1]. In the past decades, many studies have confirmed the value of routine neonatal EEG examinations in assessing brain maturity, sleep cycling, the presence and severity of encephalopathy, and seizures [2-4].
引用
收藏
页码:649 / +
页数:18
相关论文
共 67 条
[51]   NEONATAL EEG - STATISTICAL STUDIES AND PROGNOSTIC VALUE IN FULL-TERM AND PRE-TERM BABIES [J].
MONOD, N ;
PAJOT, N ;
GUIDASCI, S .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1972, 32 (05) :529-&
[52]   PERINATAL RISK-FACTORS IN CHILDREN WITH SERIOUS MOTOR AND MENTAL-HANDICAPS [J].
NELSON, KB ;
BROMAN, SH .
ANNALS OF NEUROLOGY, 1977, 2 (05) :371-377
[53]   A COMPARISON OF THE PERIOPERATIVE NEUROLOGIC EFFECTS OF HYPOTHERMIC CIRCULATORY ARREST VERSUS LOW-FLOW CARDIOPULMONARY BYPASS IN INFANT HEART-SURGERY [J].
NEWBURGER, JW ;
JONAS, RA ;
WERNOVSKY, G ;
WYPIJ, D ;
HICKEY, PR ;
KUBAN, KCK ;
FARRELL, DM ;
HOLMES, GL ;
HELMERS, SL ;
CONSTANTINOU, J ;
CARRAZANA, E ;
BARLOW, JK ;
WALSH, AZ ;
LUCIUS, KC ;
SHARE, JC ;
WESSEL, DL ;
HANLEY, FL ;
MAYER, JE ;
CASTANEDA, AR ;
WARE, JH .
NEW ENGLAND JOURNAL OF MEDICINE, 1993, 329 (15) :1057-1064
[54]   Developmental neurotoxicity of phenytoin on granule cells and Purkinje cells in mouse cerebellum [J].
Ohmori, H ;
Ogura, H ;
Yasuda, M ;
Nakamura, S ;
Hatta, T ;
Kawano, K ;
Michikawa, T ;
Yamashita, K ;
Mikoshiba, K .
JOURNAL OF NEUROCHEMISTRY, 1999, 72 (04) :1497-1506
[55]   The enigma of fetal alcohol neurotoxicity [J].
Olney, JW ;
Wozniak, DF ;
Farber, NB ;
Jevtovic-Todorovic, V ;
Bittigau, P ;
Ikonomidou, C .
ANNALS OF MEDICINE, 2002, 34 (02) :109-119
[56]   Predictive value of EEG for outcome and epilepsy following neonatal seizures [J].
Ortibus, EL ;
Sum, JM ;
Hahn, JS .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1996, 98 (03) :175-185
[57]   Phenobarbital compared with phenytoin for the treatment of neonatal seizures [J].
Painter, MJ ;
Scher, MS ;
Stein, AD ;
Armatti, S ;
Wang, ZM ;
Gardiner, JC ;
Paneth, N ;
Minnigh, B ;
Alvin, J .
NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (07) :485-489
[58]   SEIZURES IN THE PRETERM INFANT - EFFECTS ON CEREBRAL BLOOD-FLOW VELOCITY, INTRACRANIAL-PRESSURE, AND ARTERIAL BLOOD-PRESSURE [J].
PERLMAN, JM ;
VOLPE, JJ .
JOURNAL OF PEDIATRICS, 1983, 102 (02) :288-293
[59]   Non-expert use of the cerebral function monitor for neonatal seizure detection [J].
Rennie, JM ;
Chorley, G ;
Boylan, GB ;
Pressler, R ;
Nguyen, Y ;
Hooper, R .
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 2004, 89 (01) :F37-F40
[60]   The epidemiology of clinical neonatal seizures in Newfoundland: A population-based study [J].
Ronen, GM ;
Penney, S ;
Andrews, W .
JOURNAL OF PEDIATRICS, 1999, 134 (01) :71-75