Expanding the Scope of Protein Trans-Splicing to Fragment Ligation of an Integral Membrane Protein: Towards Modulation of Porin-Based Ion Channels by Chemical Modification

被引：14

作者：

Brenzel, Steffen ^{[2
]}

Cebi, Menekse ^{[1
]}

Reiss, Philipp ^{[1
]}

Koert, Ulrich ^{[1
]}

Mootz, Henning D. ^{[2
]}

机构：

[1] Univ Marburg, Fachbereich Chem, D-35032 Marburg, Germany

[2] Tech Univ Dortmund, Fak Chem Chem Biol, D-44227 Dortmund, Germany

来源：

CHEMBIOCHEM | 2009年 / 10卷 / 06期

关键词：

intein; ion channels; membrane proteins; protein modifications; protein splicing; ESCHERICHIA-COLI; OUTER MEMBRANES; INTEIN; OMPF; TRANS; TAG;

D O I：

10.1002/cbic.200900039

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

[No abstract available]

引用

页码：983 / 986

页数：4

共 27 条

[1]

Light-activated ion channels for remote control of neuronal firing [J].

Banghart, M ;

Borges, K ;

Isacoff, E ;

Trauner, D ;

Kramer, RH .

NATURE NEUROSCIENCE, 2004, 7 (12) :1381-1386

[2]

Subconductance states in OmpF gating [J].

Baslé, A ;

Iyer, R ;

Delcour, AH .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2004, 1664 (01) :100-107

[3]

Functional engineered channels and pores - (Review) [J].

Bayley, H ;

Jayasinghe, L .

MOLECULAR MEMBRANE BIOLOGY, 2004, 21 (04) :209-220

[4]

CRYSTAL-STRUCTURES EXPLAIN FUNCTIONAL-PROPERTIES OF 2 ESCHERICHIA-COLI PORINS [J].

COWAN, SW ;

SCHIRMER, T ;

RUMMEL, G ;

STEIERT, M ;

GHOSH, R ;

PAUPTIT, RA ;

JANSONIUS, JN ;

ROSENBUSCH, JP .

NATURE, 1992, 358 (6389) :727-733

[5]

SYNTHESIS OF PROTEINS BY NATIVE CHEMICAL LIGATION [J].

DAWSON, PE ;

MUIR, TW ;

CLARKLEWIS, I ;

KENT, SBH .

SCIENCE, 1994, 266 (5186) :776-779

[6]

PORIN CHANNEL TRIPLETS MERGE INTO SINGLE OUTLETS IN ESCHERICHIA-COLI OUTER MEMBRANES [J].

ENGEL, A ;

MASSALSKI, A ;

SCHINDLER, H ;

DORSET, DL ;

ROSENBUSCH, JP .

NATURE, 1985, 317 (6038) :643-645

[7]

Essen LO, 2008, ANNU REP PROG CHEM C, V104, P165, DOI 10.1039/b703980h

[8]

A light-actuated nanovalve derived from a channel protein [J].

Koçer, A ;

Walko, M ;

Meijberg, W ;

Feringa, BL .

SCIENCE, 2005, 309 (5735) :755-758

[9]

Kocer A., 2006, ANGEW CHEM, V118, P3198

[10]

Rationally designed chemical modulators convert a bacterial channel protein into a pH-sensory valve [J].

Kocer, Armagan ;

Walko, Martin ;

Bulten, Erna ;

Halza, Erik ;

Feringa, Ben L. ;

Meijberg, Wim .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (19) :3126-3130

← 1 2 3 →