A New Disubstituted Polyacetylene for the Detection of α-Amino Acids

被引：30

作者：

Zeng, Qi ^{[1
]}

Jim, Cathy K. W. ^{[2
]}

Lam, Jacky W. Y. ^{[2
]}

Dong, Yongqiang ^{[3
]}

Li, Zhen ^{[1
]}

Qin, Jingui ^{[1
]}

Tang, Ben Zhong ^{[2
]}

机构：

[1] Wuhan Univ, Dept Chem, Wuhan 430072, Peoples R China

[2] Hong Kong Univ Sci & Technol, Dept Chem, Kowloon, Hong Kong, Peoples R China

[3] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China

来源：

MACROMOLECULAR RAPID COMMUNICATIONS | 2009年 / 30卷 / 03期

基金：

美国国家科学基金会;

关键词：

amino acids; chemosensor; fluorescent reporter; metal complex; polyacetylene; LIQUID-CRYSTALLINE; CONJUGATED POLYMER; ANION RECOGNITION; RECEPTORS; HISTIDINE; CHEMOSENSOR; SELECTIVITY; ISOMERIZATION; COMPLEXATION; CATALYSTS;

D O I：

10.1002/marc.200800616

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

New imidazole-functionalized disubstituted polyacetylene was synthesized by utilizing the postfunctional strategy. In addition, its ability to sense copper ions and alpha-amino acids by fluorescence quenching has been studied. The quenching of the fluorescence of the imidazole-functionalized disubstituted polyacetylene was observed at a very low level of Cu2+ (7.0 x 10(-7) mol . L-1). The fluorescent intensity decreased rapidly upon the increase of the concentration of the added solution of Cu2+. It was expected that the addition of alpha-amino acids to the solution of the polyacetylene/Cu2+ complex could turn on the fluorescence of the polyacetylene, if a-amino acids could remove the copper ions from the complex. Glycine, was used for testing: upon the addition of glycine the quenched fluorescence of P1 turned on immediately. The detection limit was as low as 6.0 x 10(-5) mol . L-1.

引用

页码：170 / 175

页数：6

共 65 条

[61] Convenient attachment of highly polar azo chromophore moieties to disubstituted polyacetylene through polymer reactions by using "Click" chemistry [J].