Enhanced covariance spectroscopy from minimal datasets

被引：29

作者：

Chen, Yanbin

Zhang, Fengli

Bermel, Wolfgang

Brueschweiler, Rafael ^{[1
]}

机构：

[1] Florida State Univ, Dept Chem & Biochem, Natl High Magnet Field Lab, Tallahassee, FL 32306 USA

[2] Bruker BioSpin GmbH, D-76287 Rheinstetten, Germany

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 49期

关键词：

D O I：

10.1021/ja065522e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel approach is described for the determination of reliable high-resolution homonuclear NMR covariance spectra from minimal datasets. It uses a sparse sampling scheme along the indirect dimension together with a comprehensive analysis of finite sampling effects that eliminates spurious correlations. The scheme, which is demonstrated for TOCSY and COSY, offers a substantial speed up over current methods, rendering it suitable for high-throughput screening applications. Copyright © 2006 American Chemical Society.

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收藏

页码：15564 / 15565

页数：2

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