Synthesis of benz[c]benzothiopheno[2,3-e]azepines via Heck-type coupling and Pictet-Spengler reaction

被引：29

作者：

David, Emilie ^{[1
]}

Rangheard, Claudine ^{[1
]}

Pellet-Rostaing, Stephane ^{[1
]}

Lemaire, Marc ^{[1
]}

机构：

[1] Univ Lyon 1, Lab Catalyse & Synth Organ, UMR 5181, F-69622 Villeurbanne, France

来源：

SYNLETT | 2006年 / 13期

关键词：

azepine; benzo[b]thiophene; fused-ring systems; Heck reaction; Pictet-Spengler reaction;

D O I：

10.1055/s-2006-947351

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New benz[c]benzothiopheno[2,3-e]azepine derivatives 1 of potential biological properties were synthesised in four steps from bromobenzo[b]thiophene. The synthetic pathway is based on 'Heck-type' and Pictet-Spengler reactions.

引用

页码：2016 / 2020

页数：5

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