Empirical assessment of published effect sizes and power in the recent cognitive neuroscience and psychology literature

被引:445
作者
Szucs, Denes [1 ]
Ioannidis, John P. A. [2 ,3 ,4 ,5 ]
机构
[1] Univ Cambridge, Dept Psychol, Cambridge, England
[2] Stanford Univ, Meta Res Innovat Ctr Stanford METRICS, Stanford, CA 94305 USA
[3] Stanford Univ, Dept Med, Stanford, CA 94305 USA
[4] Stanford Univ, Dept Hlth Res & Policy, Stanford, CA 94305 USA
[5] Stanford Univ, Dept Stat, Stanford, CA 94305 USA
关键词
STATISTICAL POWER; SAMPLE-SIZE; P-VALUES; FMRI; FAILURE; TESTS;
D O I
10.1371/journal.pbio.2000797
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We have empirically assessed the distribution of published effect sizes and estimated power by analyzing 26,841 statistical records from 3,801 cognitive neuroscience and psychology papers published recently. The reported median effect size was D = 0.93 (interquartile range: 0.64-1.46) for nominally statistically significant results and D = 0.24 (0.11-0.42) for nonsignificant results. Median power to detect small, medium, and large effects was 0.12, 0.44, and 0.73, reflecting no improvement through the past half-century. This is so because sample sizes have remained small. Assuming similar true effect sizes in both disciplines, power was lower in cognitive neuroscience than in psychology. Journal impact factors negatively correlated with power. Assuming a realistic range of prior probabilities for null hypotheses, false report probability is likely to exceed 50% for the whole literature. In light of our findings, the recently reported low replication success in psychology is realistic, and worse performance may be expected for cognitive neuroscience.
引用
收藏
页数:18
相关论文
共 48 条
[21]   Why most discovered true associations are inflated [J].
Ioannidis, John P. A. .
EPIDEMIOLOGY, 2008, 19 (05) :640-648
[22]  
Ioannidis JPA, 2007, CLIN TRIALS, V4, P245, DOI 10.1177/1740774507079441
[23]   How to Make More Published Research True [J].
Ioannidis, John P. A. .
PLOS MEDICINE, 2014, 11 (10)
[24]   Increasing value and reducing waste in research design, conduct, and analysis [J].
Ioannidis, John P. A. ;
Greenland, Sander ;
Hlatky, Mark A. ;
Khoury, Muin J. ;
Macleod, Malcolm R. ;
Moher, David ;
Schulz, Kenneth F. ;
Tibshirani, Robert .
LANCET, 2014, 383 (9912) :166-175
[25]   Why most published research findings are false [J].
Ioannidis, JPA .
PLOS MEDICINE, 2005, 2 (08) :696-701
[26]   A survey of the statistical power of research in behavioral ecology and animal behavior [J].
Jennions, MD ;
Moller, AP .
BEHAVIORAL ECOLOGY, 2003, 14 (03) :438-445
[27]   Circular analysis in systems neuroscience: the dangers of double dipping [J].
Kriegeskorte, Nikolaus ;
Simmons, W. Kyle ;
Bellgowan, Patrick S. F. ;
Baker, Chris I. .
NATURE NEUROSCIENCE, 2009, 12 (05) :535-540
[28]   THEORY-TESTING IN PSYCHOLOGY AND PHYSICS - METHODOLOGICAL PARADOX [J].
MEEHL, PE .
PHILOSOPHY OF SCIENCE, 1967, 34 (02) :103-115
[29]   Null hypothesis significance testing: A review of an old and continuing controversy [J].
Nickerson, RS .
PSYCHOLOGICAL METHODS, 2000, 5 (02) :241-301
[30]   Promoting an open research culture [J].
Nosek, B. A. ;
Alter, G. ;
Banks, G. C. ;
Borsboom, D. ;
Bowman, S. D. ;
Breckler, S. J. ;
Buck, S. ;
Chambers, C. D. ;
Chin, G. ;
Christensen, G. ;
Contestabile, M. ;
Dafoe, A. ;
Eich, E. ;
Freese, J. ;
Glennerster, R. ;
Goroff, D. ;
Green, D. P. ;
Hesse, B. ;
Humphreys, M. ;
Ishiyama, J. ;
Karlan, D. ;
Kraut, A. ;
Lupia, A. ;
Mabry, P. ;
Madon, T. A. ;
Malhotra, N. ;
Mayo-Wilson, E. ;
McNutt, M. ;
Miguel, E. ;
Paluck, E. Levy ;
Simonsohn, U. ;
Soderberg, C. ;
Spellman, B. A. ;
Turitto, J. ;
VandenBos, G. ;
Vazire, S. ;
Wagenmakers, E. J. ;
Wilson, R. ;
Yarkoni, T. .
SCIENCE, 2015, 348 (6242) :1422-1425