Successful treatment of methicillin-resistant Staphylococcus aureus endocarditis with linezolid

被引:18
作者
Bassetti, M [1 ]
Di Biagio, A [1 ]
Del Bono, V [1 ]
Cenderello, G [1 ]
Bassetti, D [1 ]
机构
[1] Univ Genoa, Osped San Martino Genova, Clin Malattie Infett, Dept Infect Dis,Sch Med, I-16132 Genoa, Italy
关键词
MRSA; endocarditis; linezolid;
D O I
10.1016/j.ijantimicag.2003.12.018
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We report the successful treatment with linezolid of a methicillin-resistant Staphylococcus aureus (MRSA) endocarditis in a patient with a severe allergic reaction to glycopeptides. Linezolid is a drug with well-recognised activity against S. aureus and proved to be efficacious even in the unusual site of heart valves. This drug could be a good therapeutic choice when glycopeptides treatment is not feasible. (C) 2004 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
引用
收藏
页码:83 / 84
页数:2
相关论文
共 11 条
[1]   Linezolid treatment of prosthetic hip infections due to methicillin-resistant Staphylococcus aureus (MRSA) [J].
Bassetti, M ;
Di Biagio, A ;
Cenderello, G ;
Del Bono, V ;
Palermo, A ;
Cruciani, M ;
Bassetti, D .
JOURNAL OF INFECTION, 2001, 43 (02) :148-149
[2]   Critical care patients with significant, resistant, gram-postive infections enrolled in the linezolid compassionate use protocol [J].
Birmingham, MC ;
Craig, RR ;
Hafkin, B ;
Todd, WM ;
Flavin, SM ;
Root, JD ;
Zimmer, GS ;
Batts, DH ;
Schentag, JJ .
CRITICAL CARE MEDICINE, 1999, 27 (12) :A33-A33
[3]   Efficacy of linezolid alone or in combination with vancomycin for treatment of experimental endocarditis due to methicillin-resistant Staphylococcus aureus [J].
Chiang, FY ;
Climo, M .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (09) :3002-3004
[4]   Use of linezolid, an oxazolidinone, in the treatment of multidrug-resistant gram-positive bacterial infections [J].
Chien, JW ;
Kucia, ML ;
Salata, RA .
CLINICAL INFECTIOUS DISEASES, 2000, 30 (01) :146-151
[5]   Linezolid [J].
Clemett, D ;
Markham, A .
DRUGS, 2000, 59 (04) :815-827
[6]   Efficacy of linezolid in treatment of experimental endocarditis caused by methicillin-resistant Staphylococcus aureus [J].
Dailey, CF ;
Dileto-Fang, CL ;
Buchanan, LV ;
Oramas-Shirey, MP ;
Batts, DH ;
Ford, CW ;
Gibson, JK .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (08) :2304-2308
[7]   Native valve infective endocarditis in elderly and younger adult patients: Comparison of clinical features and outcomes with use of the Duke criteria and the Duke Endocarditis Database [J].
Gagliardi, JP ;
Nettles, RE ;
McCarty, DE ;
Sanders, LL ;
Corey, GR ;
Sexton, DJ .
CLINICAL INFECTIOUS DISEASES, 1998, 26 (05) :1165-1168
[8]   Successful treatment of vertebral osteomyelitis with linezolid in a patient receiving hemodialysis and with persistent methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus bacteremias [J].
Melzer, M ;
Goldsmith, D ;
Gransden, W .
CLINICAL INFECTIOUS DISEASES, 2000, 31 (01) :208-209
[9]   Linezolid therapy of Staphylococcus aureus experimental osteomyelitis [J].
Patel, R ;
Piper, KE ;
Rouse, MS ;
Steckelberg, JM .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (12) :3438-3440
[10]   INFECTIVE ENDOCARDITIS - CLINICAL-FEATURES IN YOUNG AND ELDERLY PATIENTS [J].
TERPENNING, MS ;
BUGGY, BP ;
KAUFFMAN, CA .
AMERICAN JOURNAL OF MEDICINE, 1987, 83 (04) :626-634