Anticancer effects of bioactive berry compounds

被引:93
作者
Folmer, Florence [1 ,2 ,3 ]
Basavaraju, Umesh [2 ]
Jaspars, Marcel [3 ]
Hold, Georgina [2 ]
El-Omar, Emad [2 ]
Dicato, Mario [1 ]
Diederich, Marc [4 ]
机构
[1] Hop Kirchberg, Fdn Rech Canc & Sang, Lab Biol Mol & Cellulaire Canc, L-2540 Luxembourg, Luxembourg
[2] Univ Aberdeen, Sch Med & Dent, Inst Med Sci, Div Appl Med, Aberdeen AB25 2ZD, Scotland
[3] Univ Aberdeen, Sch Nat & Comp Sci, Dept Chem, Marine Biodiscovery Ctr, Aberdeen AB24 3UE, Scotland
[4] Seoul Natl Univ, Coll Pharm, Tumor Microenvironm Global Core Res Ctr, Seoul 151742, South Korea
基金
新加坡国家研究基金会;
关键词
Anthocyanin; Anti-cancer; Anti-inflammatory; Anti-oxidant; Berry; Flavonoid; NF-KAPPA-B; TUMOR-NECROSIS-FACTOR; PUNICA-GRANATUM-L; ANTIOXIDANT CAPACITY; BLACK-RASPBERRY; TNF-ALPHA; CANCER CHEMOPREVENTION; ANTHOCYANIN-RICH; PROSTATE-CANCER; IN-VITRO;
D O I
10.1007/s11101-013-9319-z
中图分类号
Q94 [植物学];
学科分类号
071001 [植物学];
摘要
In the present review, we describe chemical and chemopreventive properties as well as health benefits of both extracts and bioactive compounds from various types of berries including small soft-fleshed edible berries and from berry-like fruits such as strawberries, raspberries, blackberries, blueberries, mulberries, currants, gooseberries, elderberries, a double dagger ai berries, and pomegranates. In particular, we describe how berry-derided phytochemicals, including anthocyanidins, proanthocyanidins, flavonols, flavanols, stilbenoids, terpenoids, ellagitannins, and ellagic acid target oxidative and UV radiation stress-induced DNA damage, Helicobacter pilori infection, pro-inflammatory as well as the major cancer hallmarks.
引用
收藏
页码:295 / 322
页数:28
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