Sepsis and Septic Shock: A History

被引：103

作者：

Funk, Duane J.

Parrillo, Joseph E. ^{[2
]}

Kumar, Anand ^{[1
,3
]}

机构：

[1] Univ Manitoba, Sect Infect Dis Med Microbiol & Pharmacol Therape, Sect Crit Care Med, Winnipeg, MB R3T 2N2, Canada

[2] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Med, Cooper Univ Hosp,Cooper Heart Inst, Camden, NJ 08103 USA

[3] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Infect Dis Sect, Sect Crit Care Med, Camden, NJ 08103 USA

来源：

CRITICAL CARE CLINICS | 2009年 / 25卷 / 01期

关键词：

Sepsis; Septic shock; History; Endotoxin; Cytokines; Coagulaiton; Nitric oxide; Sepsis hemodynamics; ACTIVATED PROTEIN-C; RANDOMIZED CONTROLLED-TRIAL; ARTERIAL SMOOTH-MUSCLE; NITRIC-OXIDE; MYOCARDIAL DYSFUNCTION; VIRUS INTERFERENCE; ANTITHROMBIN-III; RELAXING FACTOR; RELAXATION; CACHECTIN;

D O I：

10.1016/j.ccc.2008.12.003

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Infectious disease has been a leading cause of death in humans since the first recorded tabulations. From Hippocrates and Galen, to Lister, Fleming and Semmelweiss, this article reviews the notable historical figures of sepsis research. The early descriptions and theories about the etiology (microbial pathogens), pathogenesis (toxins and mediators), and treatment of sepsis-associated disease are also discussed.

引用

页码：83 / +

页数：20

共 75 条

[1] Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis -: A randomized controlled trial [J].

Abraham, E ;

Reinhart, K ;

Opal, S ;

Demeyer, I ;

Doig, C ;

Rodriguez, AL ;

Beale, R ;

Svoboda, P ;

Laterre, PF ;

Simon, S ;

Light, B ;

Spapen, H ;

Stone, J ;

Seibert, A ;

Peckelsen, C ;

De Deyne, C ;

Postier, R ;

Pettilä, V ;

Sprung, CL ;

Artigas, A ;

Percell, SR ;

Shu, V ;

Zwingelstein, C ;

Tobias, J ;

Poole, L ;

Stolzenbach, JC ;

Creasey, AA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 290 (02) :238-247

[2] Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death [J].

Abraham, E ;

Laterre, P ;

Garg, R ;

Levy, H ;

Talwar, D ;

Trzaskoma, BL ;

Francois, B ;

Guy, JS ;

Bruckmann, M ;

Rea-Neto, A ;

Rossaint, R ;

Perrotin, D ;

Sablotzki, A ;

Arkins, N ;

Utterback, BG ;

Macias, WL .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (13) :1332-1341

[3] Cytokine: more than a new word, a new concept proposed by Stanley Cohen thirty years ago [J].

不详 .

CYTOKINE, 2004, 28 (06) :242-247

[4] Pathobiology of sepsis - Are we still asking the same questions? [J].

Baron, RM ;

Baron, MJ ;

Perrella, MA .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2006, 34 (02) :129-134

[5] Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis [J].

Bernard, GR .

CRITICAL CARE MEDICINE, 2003, 31 (01) :S85-S93

[6] Efficacy and safety of recombinant human activated protein C for severe sepsis. [J].

Bernard, GR ;

Vincent, JL ;

Laterre, P ;

LaRosa, SP ;

Dhainaut, JF ;

Lopez-Rodriguez, A ;

Steingrub, JS ;

Garber, GE ;

Helterbrand, JD ;

Ely, EW ;

Fisher, CJ .

NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (10) :699-709

[7] IDENTITY OF TUMOR NECROSIS FACTOR AND THE MACROPHAGE-SECRETED FACTOR CACHECTIN [J].

BEUTLER, B ;

GREENWALD, D ;

HULMES, JD ;

CHANG, M ;

PAN, YCE ;

MATHISON, J ;

ULEVITCH, R ;

CERAMI, A .

NATURE, 1985, 316 (6028) :552-554

[8] Innate immune sensing and its roots: the story of endotoxin [J].

Beutler, B ;

Rietschel, ET .

NATURE REVIEWS IMMUNOLOGY, 2003, 3 (02) :169-176

[9] Experimental shock - The cause of the low blood pressure produced by muscle injury [J].

Blalock, A .

ARCHIVES OF SURGERY, 1930, 20 :959-996

[10] MECHANISM OF A REACTION IN VITRO ASSOCIATED WITH DELAYED-TYPE HYPERSENSITIVITY [J].

BLOOM, BR ;

BENNETT, B .

SCIENCE, 1966, 153 (3731) :80-&

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